USMLE Step 1 topics

Sample questions with full explanations from every content area of the exam. No sign-up needed — 47 topic pages, drawn from the same bank as our practice exams.

By system

The eleven content categories the Step 1 blueprint is built from.

Reproductive & Endocrine Systems

286 questions in the bank

Cardiovascular System

251 questions in the bank

Respiratory & Renal/Urinary Systems

246 questions in the bank

Multisystem Processes & Disorders

170 questions in the bank

Gastrointestinal System

155 questions in the bank

Human Development

97 questions in the bank

Blood & Lymphoreticular/Immune Systems

70 questions in the bank

By discipline

The same material cut the other way: pathology, physiology, pharmacology and the rest.

Physiology

446 questions in the bank

Pathology

379 questions in the bank

Biostatistics

274 questions in the bank

Pharmacology

268 questions in the bank

Behavioral Sciences

242 questions in the bank

Genetics

105 questions in the bank

Anatomy

102 questions in the bank

Immunology

99 questions in the bank

Microbiology

97 questions in the bank

Ethics

68 questions in the bank

Biochemistry

39 questions in the bank

Nutrition

11 questions in the bank

System and discipline together

How most people revise: one system seen through one discipline.

Biostatistics & Epidemiology Biostatistics

188 questions in the bank

Communication Skills Behavioral Sciences

127 questions in the bank

Respiratory & Renal Physiology

106 questions in the bank

Cardiovascular Physiology

95 questions in the bank

Reproductive & Endocrine Physiology

94 questions in the bank

Reproductive & Endocrine Pathology

70 questions in the bank

Musculoskeletal & Skin Pathology

69 questions in the bank

Behavioral & Nervous Pharmacology

67 questions in the bank

Behavioral & Nervous Behavioral Sciences

66 questions in the bank

Communication Skills Ethics

66 questions in the bank

Cardiovascular Pharmacology

61 questions in the bank

Gastrointestinal Pathology

52 questions in the bank

Reproductive & Endocrine Pharmacology

52 questions in the bank

Respiratory & Renal Pathology

50 questions in the bank

Cardiovascular Pathology

47 questions in the bank

Behavioral & Nervous Physiology

46 questions in the bank

Human Development Behavioral Sciences

41 questions in the bank

Behavioral & Nervous Pathology

40 questions in the bank

Multisystem Genetics

39 questions in the bank

Gastrointestinal Physiology

37 questions in the bank

Multisystem Pathology

33 questions in the bank

Blood & Immune Immunology

31 questions in the bank

Behavioral & Nervous Anatomy

30 questions in the bank

Respiratory & Renal Pharmacology

30 questions in the bank